Bioactive Small Molecules
Medchemexpress LLC Rasagiline mesylate | 161735-79-1 | MFCD08460604 | 99.8% | 267.34 g/mol | C13H17NO3S | 5 MG
Rasagiline mesylate is a selective, irreversible monoamine oxidase (MAO) inhibitor provided for research applications. It is used in neuroscience and enzymatic assays to study MAO-B activity and is supplied in small solid and solution formats with analytical-grade purity.
- Selective irreversible MAO inhibitor suitable for research assays.
- High purity (99.82%) for analytical applications.
- Available in small solid quantities and standard solutions.
- Molecular weight 267.34 g/mol and formula C13H17NO3S.
- Suitable for MAO-B inhibition and neuroscience studies.
Enzo Life Sciences Amidepsine A (2.5mg). CAS: 169181-28-6
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=10.2µM) and Raji cells (IC50=15.5µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders. Purity: ≥95% (HPLC). Appearance: Pale white to pale yellow powder. Solubility: Soluble in methanol, ethyl acetate or benzene; insoluble in water or hexane. Long Term Storage: -20°C.
Medchemexpress LLC Copper(II) Gluconate | 527-09-3 | 98.0% | 453.84 | 1 ML
Copper(II) Gluconate is a non-toxic copper supplement aid and the copper salt of D-gluconic acid. It can be used as a precursor catalyst in the photo-induced polymerization of acrylates. This product is provided as a 10 mM solution in 1 mL of DMSO.
- Can serve as a catalyst precursor for controlled polymerization of acrylate monomers.
- Ligand exchange can be accelerated by ultraviolet irradiation or elevated temperature.
- Suitable for in vitro research.
Cayman Chemical JNJ-42153605, Purity: ≥98%, CAS: 1254977-87-1, 5 mg
A positive allosteric modulator of mGlurR2 (EC50 = 17 nM in CHO cells expressing the human receptor); inhibits mGluR2-mediated REM sleep in rats at 3 mg/kg; reverses phencyclidine-induced hyperlocomotion in mice (ED50 = 5.4 mg/kg)
Cayman Chemical AF-DX 116, Purity: ≥98%, CAS: 102394-31-0, 1 mg
A muscarinic M2 receptor antagonist (Ki = 0.2 µM); selective for cardiac M2 over salivary gland M3 receptors (Ki = 5.01 µM) but also binds sympathetic ganglia M1 receptors (Ki = 0.81 µM); increases vagus nerve stimulation-induced increases in perfusion pressure by 50% in isolated perfused rat hearts at 0.1 µM; increases systolic blood pressure and heart rate in a rat model of hypotension induced by repeated cold stress at 50, 100, and 200 µg/kg
Medchemexpress LLC Ncgc 607 | 1462267-07-7 | 99.5% | 5 MG
NCGC 607 is a small-molecule, noninhibitory chaperone of glucocerebrosidase (GCase) used for research applications; it has been reported to increase GCase activity and reduce α-synuclein, making it relevant to studies of Gaucher disease and synucleinopathies.
- Noninhibitory glucocerebrosidase chaperone.
- Increases GCase activity and protein levels.
- Reduces α-synuclein and glycolipid accumulation.
- High purity (99.53%) suitable for research assays.
- Small-molecule, solid form; soluble in DMSO for biochemical use.
Apexbio Technology LLC Biotin-HPDP, 50mg. Cas: 129179-83-5 MFCD: MFCD00078541. Sulfhydryl-reactive biotinylation reagent, pyridyldithiol-activated
Biotin-HPDP (N-[6-(biotinamido)hexyl]-3-(2-pyridyldithio)propionamide), a sulfhydryl-reactive biotinylation agent, is a water-insoluble reagent that requires the dissolution of suitable solvents, including dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). Other sizes are available. Please inqury us for quote.
![Medchemexpress LLC [1-(3-Methylphenyl)benzimidazol-5-yl]-piperidin-1-ylmethanone | 451496-96-1 | MFCD04422127 | 99.8% | 319.4 g/mol | C20H21N3O | 10MM 1ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237028.png-250.jpg)
Medchemexpress LLC [1-(3-Methylphenyl)benzimidazol-5-yl]-piperidin-1-ylmethanone | 451496-96-1 | MFCD04422127 | 99.8% | 319.4 g/mol | C20H21N3O | 10MM 1ML
ML148 is a potent and selective inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) used as a research reagent to probe prostaglandin-signaling pathways. The compound is available as a 10 mM solution in DMSO or as solid material in multiple mass sizes. Reported IC50 against 15-PGDH is 56 nM. Molecular formula C20H21N3O; molecular weight 319.4 g/mol; reported purity ~99.8%.
- Potent and selective 15-PGDH inhibitor, IC50 56 nM.
- Offered as 10 mM DMSO solution and as solid quantities for flexibility in assays.
- High purity (~99.8%) suitable for biochemical and cell-based research.
- Well-characterized chemical identity: C20H21N3O, 319.4 g/mol.
- Supplied with spectral and analytical data for quality assurance.
Medchemexpress LLC Isomannide (1,4:3,6-dianhydromannitol) | 641-74-7 | MFCD10698761 | 99.9% | 500g
Isomannide (1 4 3 6-Dianhydromannitol) is a common intermediate compound and derivative of Isosorbide (HY-B1469) Some derivatives of isomannide have potent inhibitory effects on KLK5 and KLK7 Isomannide can be used in the research of HCV infection and KLK5/KLK7-related diseases[1][2][3]
eMolecules 59474-01-0 | Medchem Express | NSC 146109 (hydrochloride) | 5mg | 673358662 | HY-108638 | MFCD09878281 | 316.85 | C17H17ClN2S
Medchem Express | NSC 146109 (hydrochloride) | 5mg | 673358662 | HY-108638 | 59474-01-0 | MFCD09878281 | 316.850 | C17H17ClN2S
Medchemexpress LLC Estra-1,3,5(10)-trien-17-one, 3-(sulfooxy)-, compd. with piperazine (1:1) | 7280-37-7 | 98.7% | 1 ML
Estropipate is a form of estrogen, used to treat symptoms of menopause, also used to prevent osteoporosis.
- CAS number: 7280-37-7
- Molecular formula: C₂₂H₃₂N₂O₅S
- Molecular weight: 436.56
- Target: Estrogen Receptor/ERR
- Pathway: Vitamin D Related/Nuclear Receptor
- Storage (solid): 4°C, sealed storage, away from moisture
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month (sealed storage, away from moisture)
- Appearance: White to off-white solid
- Purity: 98.72%
- In vitro solubility (DMSO): 110 mg/mL (251.97 mM)
Cayman Chemical BMS 986158, Purity: ≥98%, CAS: 1800340-40-2, 25 mg
A BET bromodomain inhibitor; decreases c-Myc expression and induces cancer cell death in c-Myc-driven cancer cell lines in vitro; inhibits tumor growth in triple-negative breast, colorectal, and lung cancer patient-derived mouse xenograft models
Cayman Chemical CAY10760, Purity: ≥98%, CAS: 391889-85-3, 1 mg
An inhibitor of the RAD51-BRCA2 protein-protein interaction (EC50 = 19 µM in a cell-free competitive ELISA); decreases homologous recombination by 54% in BxPC-3 pancreatic cancer cells at 20 µM; decreases proliferation of BxPC-3 and Capan-1 cancer cells when used alone or in combination with olaparib
Medchemexpress LLC Gsk3β inhibitor II | 478482-75-6 | 99.5% | 395.22 | 25 MG
Gsk3β inhibitor II is an inhibitor of Gsk3β and can be used for research related to Alzheimer's disease (AD). It demonstrates specific interactions within biological systems, contributing to its inhibitory action.
- Forms hydrogen bonds with Val135
- Exhibits hydrophobic interaction with Ile62, Phe67, Val70, Ala83, and Leu188
- Shows ionic interaction with Lys85
- Can be used for Alzheimer's disease research
Medchemexpress LLC Azalamellarin N | 1809535-57-6 | 99.6% | 498.48 | 25 MG
Azalamellarin N is an inhibitor of pyroptosis and has different inhibitory effects on different pyroptosis inducers. It inhibits pyroptosis by targeting molecules that act upstream of NLRP3 inflammasome activation, rather than directly targeting components of the NLRP3 inflammasome.
- Inhibits pyroptosis by targeting molecules upstream of NLRP3 inflammasome activation.
- Does not directly target components of the NLRP3 inflammasome.
- Inhibitory potency against different pyroptosis inducers: nigericin > R837.